Thomas Frazier
Professor
Background
Through my career, I have been interested in clinical assessment, behavioral neuroscience, and psychopathology. The overarching themes of my research are understanding, assessing, and treating individuals with autism and other forms of psychopathology.
Areas of Expertise
- Psychological Assessment
Research Interests
My research focuses on developing new measurement tools for autism spectrum disorder (ASD) and related developmental and neurogenetic conditions. I develop tools across modalities, including traditional questionnaires, online cognitive and behavioral assessments, and webcam-collected performance measures.
Education
Ph.D., M.A., Clinical Psychology, Case Western Reserve University B.S., Psychology, John Carroll UniversityCourses Taught
PS 1000 Introductory PsychologyPS 2100 Sports Psychology
PS 3010 / 3011 Experimental Design and Lab
Publications
Baker EK, Frazier TW, Phillips JM, Hardan AY, Uljarevic M. Characterizing Key Correlates of Sleep Problems Across Rare Neurodevelopmental Genetic Disorders. J Autism Dev Disord. 2025 Dec;55(12):4480-4491. doi: 10.1007/s10803-025-07069-3. Epub 2025 Oct 25. PubMed PMID: 41138043.
Chetcuti L, Hardan AY, Frazier TW, Loth E, McPartland JC, Youngstrom EA, Uljarevic M. Advancing scientific understanding of the drive to socially engage: from broad constructs to transdiagnostic 'building blocks'. Mol Psychiatry. 2025 Aug 26;. doi: 10.1038/s41380-025-03185-9. [Epub ahead of print] Review. PubMed PMID: 40858780.
Chetcuti L, Hardan AY, Spackman E, Loth E, McPartland JC, Frazier TW, Youngstrom EA, Uljarevic M. Parsing the heterogeneity of social motivation in autism. J Child Psychol Psychiatry. 2025 Sep;66(9):1376-1389. doi: 10.1111/jcpp.14147. Epub 2025 Mar 16. PubMed PMID: 40091308; PubMed Central PMCID: PMC12353203.
Chetcuti LC, Spackman EK, Frazier TW, Whitehouse AJO, Uljarevic M. The autism phenotype and transdiagnostic dimensional frameworks. Dev Med Child Neurol. 2025 Sep;67(9):1130-1136. doi: 10.1111/dmcn.16303. Epub 2025 Mar 24. Review. PubMed PMID: 40126448.
Chetcuti L, Uljarevic M, Schuck RK, Hardan AY, Gengoux GW, Trembath D, Vadgama Y, Varcin KJ, Vivanti G, Whitehouse AJO, Helton M, Frazier TW. Characterizing predictors of response to behavioral interventions for children with autism spectrum disorder: A meta-analytic approach. Clin Psychol Rev. 2025 Jul;119:102588. doi: 10.1016/j.cpr.2025.102588. Epub 2025 May 3. PubMed PMID: 40347530.
Chetcuti L, Hardan AY, Spackman E, Baker E, Frazier TW, Uljarevic M. Factor Structure and Psychometric Properties of the Child Social Preference Scale-3 in Children With Autism. Autism Res. 2025 May 26;. doi: 10.1002/aur.70059. [Epub ahead of print] PubMed PMID: 40415716.
Chen YJ, Frazier TW, Szatmari P, Duku E, Richard AE, Smith IM, Zwaigenbaum L, Bedford R, Kerns CM, Zaidman-Zait A, Bennett T, Elsabbagh M, Vaillancourt T, Georgiades S. Sex-Differential Trajectories of Domain-Specific Associations Between Autistic Traits and Co-Occurring Emotional-Behavioral Concerns in Autistic Children. Autism Res. 2025 Apr;18(4):820-832. doi: 10.1002/aur.70018. Epub 2025 Mar 14. PubMed PMID: 40083203; PubMed Central PMCID: PMC12015799.
Dhawan A, Liu D, Baitamouni S, Anthony K, Srivastava S, Hardan AY, Uljarevic M, Lachlan KL, Frazier TW, Busch RM, Eng C. Neurodevelopmental and Neurologic Manifestations of PTEN Hamartoma Tumor Syndrome: Management Recommendations. Neurol Genet. 2025 Oct;11(5):e200299. doi: 10.1212/NXG.0000000000200299. eCollection 2025 Oct. Review. PubMed PMID: 41080814; PubMed Central PMCID: PMC12509708.
Farmer C, Thurm A, Das T, Bebin EM, Bernstein JA, Berry-Kravis E, Buxbaum JD, Eng C, Frazier T, Hardan AY, Kolevzon A, Krueger DA, Martinez-Agosto JA, Northrup H, Powell CM, Valluripalli Soorya L, Wu JY, Sahin M. Which Score for What? Operationalizing Standardized Cognitive Test Performance for the Assessment of Change. Am J Intellect Dev Disabil. 2025 Sep 1;130(5):344-361. doi: 10.1352/1944-7558-130.5.344. PubMed PMID: 40858311.
Ferguson EF, Frazier TW, Hardan AY, Uljarevic M. Challenging Behavior Domains in Individuals With Neurodevelopmental Genetic Syndromes: The Role of Psychological Features. Am J Med Genet B Neuropsychiatr Genet. 2025 Aug 20;. doi: 10.1002/ajmg.b.33049. [Epub ahead of print] PubMed PMID: 40833200.
Ferguson EF, Russell KM, Licona SJ, Cai RY, Frazier TW, Vivanti G, Gengoux GW, Hardan AY, Uljarevic M. Toward improved understanding and treatment of self-injurious behaviors in autistic individuals with profound intellectual disability. Autism Res. 2025 Feb;18(2):261-272. doi: 10.1002/aur.3289. Epub 2024 Dec 17. Review. PubMed PMID: 39688125.
Frazier TW, Helton M, Akouri C, Chetcuti L, Uljarevic M. Identifying reliable change in outcome assessments for behavioral interventions. Behavioral Interventions. 2025;40:e70007. doi:https://doi.org/10.1002/bin.70007
Frazier TW, Huba, K, Frazier, AR, Womack, RA, Youngstrom, EA, Chetcuti, C. Maximizing accurate detection of divergence from normative expectation in behavioral intervention outcome assessment. Research in Autism. 2025;126:202646. doi:https://doi.org/10.1016/j.reia.2025.202646
Frazier TW, Youngstrom EA, Frazier AR, Uljarevic M. A Critical Appraisal of the Measurement of Adaptive Social Communication Behaviors in the Behavioral Intervention Context. Behavioral Sciences. 2025;15(6):722. doi:https://doi.org/10.3390/bs15060722
Frazier TW, Chetcuti L, Uljarevic M. Evidence That Intervention Dosage Is Associated With Better Outcomes in Autism. JAMA Pediatr. 2025 Jan 1;179(1):101-102. doi: 10.1001/jamapediatrics.2024.4710. PubMed PMID: 39495536.
Frazier TW, Dimitropoulos A, Abbeduto L, Armstrong-Brine M, Kralovic S, Shih A, Hardan AY, Youngstrom EA, Uljarevic M. Psychometric evaluation of the Autism Symptom Dimensions Questionnaire. Dev Med Child Neurol. 2025 Jun;67(6):758-769. doi: 10.1111/dmcn.16200. Epub 2024 Dec 19. PubMed PMID: 39699005; PubMed Central PMCID: PMC12066973.
Spackman E, Chetcuti L, Baker EK, Ferguson EF, Yerys BE, Herrington JD, Frazier TW, Leekam SR, Hardan AY, Harrington JW, Uljarevic M. Transdiagnostic Examination of Interrelationships Between Anxiety, Insistence on Sameness and Compulsions. Autism Res. 2025 Oct;18(10):1991-1998. doi: 10.1002/aur.70096. Epub 2025 Jul 30. PubMed PMID: 40878890.
Frazier TW, Busch RM, Klaas P, Lachlan K, Loth E, Smith-Hicks C, Sahin M, Hardan AY, Uljarevic M. Quantifying neurobehavioral profiles across neurodevelopmental genetic syndromes and idiopathic neurodevelopmental disorders. Dev Med Child Neurol. 2025 May;67(5):618-629. doi: 10.1111/dmcn.16112. Epub 2024 Nov 11. PubMed PMID: 39526825; PubMed Central PMCID: PMC11965975.
Frazier T. Autism screening is critical for the most vulnerable children. Dev Med Child Neurol. 2025 Mar;67(3):279-280. doi: 10.1111/dmcn.16043. Epub 2024 Aug 21. PubMed PMID: 39166419; PubMed Central PMCID: PMC11794666.
